Group testing as a strategy for COVID-19 epidemiological monitoring and community surveillance

نویسندگان

چکیده

Sample pooling consists in combining samples from multiple individuals into a single pool that is then tested using unique test-kit. A positive test means at least one individual within the infected. Here, we propose an analysis and applications of sample to epidemiologic monitoring COVID-19. We first introduce model RT-qPCR process used for presence virus construct statistical viral load typical infected inspired by clinical data Jones et. al. (2020). method measure prevalence population, based on group testing, taking account increased number false negatives associated with this method. Finally, present application prevention epidemic outbreak closed connected communities (e.g. nursing homes).

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ژورنال

عنوان ژورنال: PLOS Computational Biology

سال: 2021

ISSN: ['1553-734X', '1553-7358']

DOI: https://doi.org/10.1371/journal.pcbi.1008726